Description of Duphaston Tablet

Duphaston Tablet is a hormonal medication. It has a similar action to the female hormone known as progesterone. It is used for the treatment of menstrual conditions such as unusual menstrual bleeding or pain, irregular periods, and premenstrual syndrome (physical and emotional changes experienced by some women a few days before menstruation). Duphaston Tablet is also used to treat endometriosis (growth of tissue outside the womb), female infertility, threatened abortions (vaginal bleeding that occurs in the first 20 weeks of pregnancy), or habitual abortion (three or more consecutive pregnancy losses). This medicine is used as a component in hormone replacement therapy (a treatment to relieve symptoms of menopause).

Duphaston Tablet works by imitating the activities of the natural hormone progesterone, which in turn helps to treat conditions caused due to hormonal imbalance in the body.

Duphaston Tablet may cause side effects such as nausea, headache, abnormal vaginal discharge, breast pain and tenderness, etc. These side effects usually subside with time. However, consult your doctor for further assistance if they persist or worsen. Avoid driving vehicles or operating heavy machines if you feel dizzy or drowsy after taking this medicine.

Duphaston Tablet can be taken with or without food. Take the medication at the same time every day for ease of remembering. Do not discontinue the medication without consulting your doctor. Follow the instructions given by your doctor about the dose and duration of the treatment.

Duphaston Tablet is not recommended if you are allergic to it. It should be avoided if you have undiagnosed vaginal bleeding, serious liver conditions, or a progesterone-dependent tumour (a type of cancer that is dependent on progesterone for growth and/or survival). Inform your doctor if you have porphyria (abnormalities in the production of an oxygen-carrying chemical known as haeme, due to the accumulation of porphyrins in the body), depression, or other medical conditions.

Duphaston Tablet should be taken during pregnancy only upon your doctor’s advise. It is not recommended for use while breastfeeding due to the lack of safety information. This medicine is not recommended for use in children below 18 years of age.

Side effect

  • Nausea
  • Abdominal pain
  • Vomiting
  • Diarrhoea
  • Dry mouth
  • Indigestion
  • Rash
  • Itching
  • Cough
  • Breast pain
  • Depression
  • Mood swings
  • Difficulty in falling asleep
  • Headache
  • Dizziness
  • Drowsiness
  • Breast tenderness
  • Weight gain
  • Abnormal and/or painful menstruation

Uses of Duphaston Tablet

  • Dysmenorrhoea
  • Endometriosis
  • Secondary Amenorrhoea
  • Menstrual abnormalities
  • Dysfunctional uterine bleeding
  • Threatened abortion (bleeding occurring in during pregnancy)
  • Habitual abortion
  • Infertility due to luteal Insufficiency (infertility due to lack of progesterone hormone)
  • Hormone replacement therapy

Concerns

How long does it take for this medicine to take effect?

The time required for Duphaston Tablet to show its effect is not clinically established.

How long do the effects of this medicine last?

The time duration for which Duphaston Tablet remains effective in the body is clinically not established.

Is it safe to consume alcohol while taking this medicine?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?

No habit-forming tendencies were reported for Duphaston Tablet.

Can this medicine be taken during pregnancy?

Duphaston Tablet should be used during pregnancy upon your doctor’s recommendation.

Can this medicine be taken while breast-feeding?

It is not known whether Duphaston Tablet passes into breast milk or if it could affect the nursing baby. Hence consult your doctor if you are breastfeeding.

When not to use?

Allergy

Avoid taking Duphaston Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Undiagnosed vaginal bleeding

Duphaston Tablet is not recommended for use if you have abnormal vaginal bleeding that has not been diagnosed by a doctor, as it may worsen your health condition.

Progesterone-dependent cancer

Duphaston Tablet is not recommended for use if you have progesterone-dependent cancer (a type of cancer that is dependent on progesterone for growth and/or survival) such as breast or uterus cancer.

Severe liver disease

Duphaston Tablet is not recommended for use if you have severe liver problems as it may further worsen your condition.

Warnings

Warnings for special population

Pregnancy

Duphaston Tablet should be used during pregnancy upon your doctor’s recommendation.

Breast-feeding

It is not known whether Duphaston Tablet passes into breast milk or if it could affect the nursing baby. Hence consult your doctor if you are breastfeeding.

General warnings

Driving or operating machines

Duphaston Tablet may cause dizziness or drowsiness in some cases. Hence, do not perform activities that require mental alertness, such as driving vehicles or operating machines, if you experience any of these symptoms.

Use in children

Duphaston Tablet is not recommended for use in children below 18 years of age due to the lack of safety and efficacy data.

Liver diseases

Duphaston Tablet should be used with caution if you have liver problems, as it can worsen your condition. Follow all the instructions given by your doctor.

Porphyria

Duphaston Tablet should be used with caution if you have porphyria (abnormalities in the production of an oxygen-carrying chemical known as haeme, due to accumulation of porphyrins in the body), as it can worsen your condition. Follow all the instructions given by your doctor.

Depression

Duphaston Tablet should be used with caution if you have depression (a feeling of sadness for a long period and loss of interest in daily activities), as it can worsen your condition. Follow all the instructions given by your doctor. Consult your doctor if you experience changes in mood or behaviour.

Dosage

Missed Dose

Do not miss the dose of Duphaston Tablet. In case you miss a dose, take it as soon as you remember. However, if it is time for the next dose, then skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of Duphaston Tablet. Seek emergency medical treatment in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Phenobarbital
Nevirapine
Rifampicin
Ritonavir
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions

General Instructions

Duphaston Tablet can be taken with or without food. Take the medication at the same time every day for ease of remembering.

Follow all the instructions advised by your doctor while taking the medicine. Do not take this medicine in larger or smaller quantities than advised.

A regular follow-up visit with your doctor is recommended during treatment with this medicine so that he/she can evaluate your condition.

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